Akame is white Kishu and wear black eye patch.
It's unknown whether or not one of his eyes is blind.
His master was killed by Nobunaga Oda's men and Koga ganins who had joined them. Akame ran and brought the secret technique scrolls to the master's son Kotaru. A year after this, Akame had his revenge as he managed to kill Nobunaga during the chaos caused by Akechi Mitsuhide, Nobunaga's traitorous vassal.
Akame stayed with Kotaru who loved the dog like his father and thus the Itou family carried on existing.